Honden (Main Building), Heiden (Votive Offering Hall) and Haiden (Worship Hall) are designated as registered tangible cultural properties. Honden is a well-balanced pavilion of Kirizuma-zukuri (an architectural style with a gabled roof). The structure of Heiden is Ryousage-zukuri, and in contrast to Honden, many sculptures can be seen. Haiden is Irimoya-zukuri (a half-hipped gable roof), skillful techniques can be seen in the ornaments in front of the building. The origin of the shrine is when Sukunahikona-no-mikoto was invited from Gojyouten-Shinsha in Kyoto and worshipped him with Shinnou-Entei in 1780, Along with the Aothecary Museum by the shrine office, The shrine bears a very important role as the spiritual place to rely on for medical traders in Dosho-Machi.